Open Access Conference Proceedings

Abstract: Platinum-based cytostatic represent a unique class of DNA-damaging antitumor agents and they are one the most frequently used drugs in oncology. Problem is that some kind of cancer is resistant against this type of cytostatics. [..] Read more

Abstract: Cisplatin (cis-diamminedichloroplatinum II) is cytostatic currently used in the treatment of a various type of solid tumors, including cancers of the ovary, testis, bladder, head and neck, lung, cervix and endometrium. The health effects of platinum are strongly dependent upon the kind of bonds that are shaped and the exposure level and immunity of the person that is exposed. [..] Read more

Abstract: Corneal damage is one of the most common causes of impaired vision or even blindness. When the injury is more extensive and the limbal region is involved, the natural regeneration of the cornea is not sufficient. [..] Read more

Abstract: Paper tests are very cheap and fast diagnostic tools for self-testing in a wide range of health problems. Thus, the diagnostics of tumor development is of a great medical and socio-economic significance. [..] Read more

Abstract: Sarcosine is an amino acid that is formed by methylation of glycine and is present in trace amounts in the body. Increased sarcosine concentrations in blood plasma and urine are associated with sarcosinemia and some other diseases such as prostate cancer. [..] Read more

Abstract: Target therapy for oncologic diseases presents a big challenge for advance nanomedicine. In our work, we focused on multi-target approach development. [..] Read more

Abstract: Photodynamic therapy is a relatively new type of cancer treatment, or eventually it is used at the elimination of undesirable pathogenic microorganisms. Quantum dots (QDs) are semiconducting nanocrystals with a size of 2-20 nm and can be used in photodynamic therapy. [..] Read more

Abstract: This work is focused on the preparation and characterization of nanoparticles. Particles were prepared from negatively charged polymer – sodium hyaluronate and oppositely charged polyaminoacid – polyarginine hydrochloride in water and 0.15 M sodium chloride. [..] Read more

Abstract: Aim of this work deals with closing of cisplatin into liposomes, the study of their stability and interaction with cancer cell lines. Commercial cisplatin cytostatic was encapsulated into three types of liposomes (L8, L10 and L15) of a different chemical composition. [..] Read more

Abstract: The synthesis process of composites based on graphene oxide is described and tested as a carrier of zinc oxide nanoparticles and subsequently tested as an antimicrobial agent for some bacterial strains (Staphylococcus aureus (S. aureus), methicillin-resistant Staphylococcus aureus (MRSA) and Escherichia coli (E. [..] Read more

Abstract: The production of renewable, biobased and biodegradable bionanocomposites is dicussed in current research. The developement of such materials is mainly driven by rising concerns over environmental issues, sustainability and dependency on decreasing petroleum resources. [..] Read more

Abstract: In recent days, advancements in nanotechnology ensure everyday applications of nanostructured noble metals, especially silver. Particularly in the medicinal applications, where they profit from their unique antibacterial effects, a serious risk of cytotoxic side-effects may occur. [..] Read more

Abstract: The present work is focused on preparation of chitosan films, which were doped with silver nanoparticles (AgNPs). AgNPs were prepared and stabilized by reduction of silver nitrate by chitosan without addition of other reducing agents. [..] Read more

Abstract: A conformal coating of a thin diamond layer on three-dimensional metal bone implants was shown directly on stainless steel and TiAl6V4 cortical screw implant using ultrasonic and composite polymer pretreatment method. The best conformation coverage was achieved in the case of the WO3 interlayer for both stainless steel and TiAl6V4 screws. [..] Read more

Abstract: In the presented work the simultaneous use of ultrasound in tracking and smart release was investigated. Hybrid microparticles based on an iron core coated by a polysaccharide were prepared and loaded with doxorubicin. [..] Read more

Abstract: Adsorption of antibodies to tularemia Francisella tularensis (F. name of the genus) on the surface of gold-plated glass chips and the subsequent reaction of antigen-antibody were studied by surface plasmon resonance (SPR) technique. [..] Read more

Abstract: Extracellular matrix (ECM) forms an essential part of tissue microenvironment. Compositional and structural properties of ECM modulate behaviour of cells, including their differentiation, proliferation, and turnover. [..] Read more

Abstract: Nanofibrous matrices represent an attractive material for biomedical applications – mainly due to their high specific surface and small pore size, which make them interesting material for drug delivery matrixes construction. Besides the morphological characteristics, the surface functionality strongly affects the drug-matrix interaction, drug conjugation and drug release kinetics. [..] Read more

Abstract: The present article deals with the problematic of so called green synthesis of iron oxide nanoparticles. The iron oxide nanoparticles can be used e.g. [..] Read more

Abstract: Cells labelled with iron oxide nanoparticles (ION) can be tracked by magnetic resonance imaging (MRI) in several applications. However, various studies demonstrated toxicity and oxidative stress induction associated with nanoparticles exposure. [..] Read more