from the conferences organized by TANGER Ltd.
Worldwide production and consumption of pharmaceuticals increases every year. Due to the fact that these substances are not always completely eliminated in the human or animal body, subsequently get into the environment, which leads to a negative effect of certain constituents of natural ecosystems. Knowledge of contaminant behaviour is essential for their mobility and toxicity in the soils and surface- and ground-water environments. In this study, interactions of pharmaceuticals with soils and humic substances as the most important constituents of soil organic matter are investigated. Humic substances contain more types of active sites (hydrophilic functional groups and hydrophobic structures) able to bind different drugs and form relatively stable complexes with them. The complexation of drugs with soil organic matter thus can reduce their mobility and toxicity in natural systems. This study deals with interactions of soils and humic substances with drugs. the aim is to determine their binding capacity and stability of formed complexes with respect to the possible immobilization of drugs in the humic structure.
Keywords: Humic acids, soil, ibuprofen, stability© This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.