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ZINC PHOSPHATE NANOPARTICLES PREPARATION AND THEIR ANTIMICROBIAL ACTIVITY

1,2 KOPEL Pavel
Co-authors:
1,2 CERNEI Natalia 1 GAGIC Milica 3 HORKY Pavel 1,2 SMERKOVA Kristyna 1,2 ADAM Vojtech
Institutions:
1 Department of Chemistry and Biochemistry, Faculty of Agronomy, Mendel University in Brno, Zemedelska 1, CZ-613 00 Brno, Czech Republic, EU, E-mail: vojtech.adam@mendelu.cz
2 Central European Institute of Technology, Brno University of Technology, Purkynova 123, CZ-612 00 Brno, Czech Republic, EU
3 Department of Animal Nutrition and Forage Production, Faculty of Agronomy, Mendel University in Brno, Zemedelska 1, CZ-613 00 Brno, Czech Republic, EU
Conference:
10th International Conference on Nanomaterials - Research & Application, Hotel Voronez I, Brno, Czech Republic, EU, October 17th - 19th 2018
Proceedings:
Proceedings 10th International Conference on Nanomaterials - Research & Application
Pages:
489-493
ISBN:
978-80-87294-89-5
ISSN:
2694-930X
Published:
28th February 2019
Proceedings of the conference were published in Web of Science and Scopus.
Metrics:
545 views / 351 downloads
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Abstract

Zinc phosphate particles were prepared by reaction of zinc nitrate with hydrogen phosphate, diphosphate and triphosphate, and characterized by Dynamic Light scattering (DLS) and Scanning Electron Microscopy (SEM). Antibacterial effect of ZnO nanoparticles and zinc phosphates ones were compared. Bacterial strains of (Escherichia coli NCTC 13216, Staphylococcus aureus NCTC 8511, and Methicillin-resistant S. aureus CCM 7110 were used for the testing. Oxidative stress was determined the GSH/GSSG ratio by using High-pressure liquid chromatography with twelve-channel CoulArray electrochemical detector (HPLC-ED). It has been demonstrated the zinc phosphate particles shown better antibacterial properties and smaller toxicity, than the conventional ZnO.

Keywords: Zinc phosphate, Zinc oxide, Antimicrobial properties

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