from the conferences organized by TANGER Ltd.
Biocompatible and bactericidal coatings were deposited onto different titanium based implant materials. For this the plasma chemical oxidation (PCO) process as well as the atmospheric pressure plasma chemical vapour deposition (APCVD) was used successively. With the PCO technique about 10 µm thick oxide films with high amounts of amorphous calcium phosphate and a defined morphology structure can be deposited onto the titanium implant substrates. It can be shown that the morphological structure and the film composition have a positive influence on the adhesion and the growth of human cells, tested with HaCaT keratinocytes and therefore are suited to improve the biocompatibility compared to pure metals or alloys. With the APCVD thin composite SiOx films can be deposited on the modified titanium substrates. Silver, copper or zinc was used as bactericidal agent, the APCVD film thickness is in the range of less than 150 nm. It could be shown that the bactericidal efficiency of these composite coatings depends slightly on the amount of agent in the films, the agent itself and the used bacteria strains with their specific cell structure. For both of the shown agents Ag and Cu a therapeutic range could be determined, without cytotoxic but bactericidal properties. Beside the description of the coating processes and test methods diverse film properties like structural images as well as the bactericidal and cytotoxic behaviour of the coatings will be presented.
Keywords: Plasma chemical oxidation (PCO), Atmospheric pressure plasma chemical vapour deposition (APCVD), implant materials, titanium alloys, bactericidal behaviour© This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.